METHADONE HYDROCHLORIDE vs ORLAAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. METHADONE HYDROCHLORIDE and ORLAAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	METHADONE HYDROCHLORIDE	ORLAAM
Rating	72/100	New
Pharmacy pays	$0.18 /mL	—
Type	RX	RX
Active ingredient	METHADONE HYDROCHLORIDE	LEVOMETHADYL ACETATE HYDROCHLORIDE
Manufacturer	Hikma	Roxane
Dosage forms	Injectable, Solution, Tablet	—
Drug class	Opioid Agonist	—
Boxed warning	Boxed warning	None
Half-life	about 8 to 59 hours (terminal/elimination half-life; a very wide range)	—
Treats	Opioid-Related Disorders, Intractable Pain	Opioid-Related Disorders

methadone hydrochloride orlaam

Rating

72/100

New

Pharmacy pays

$0.18 /mL

—

Type

Active ingredient

METHADONE HYDROCHLORIDE

LEVOMETHADYL ACETATE HYDROCHLORIDE

Manufacturer

Hikma

Roxane

Dosage forms

Injectable, Solution, Tablet

—

Drug class

Opioid Agonist

—

Boxed warning

None

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)

—

Treats

Opioid-Related Disorders, Intractable Pain

Opioid-Related Disorders

Frequently asked questions

What is the difference between Methadone Hydrochloride and Orlaam?

Methadone Hydrochloride contains Methadone Hydrochloride, while Orlaam contains Levomethadyl Acetate Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.