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METHADONE HYDROCHLORIDE vs ORLAAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. METHADONE HYDROCHLORIDE and ORLAAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

methadone hydrochlorideorlaam

Rating

72/100
70/100

Pharmacy pays

$0.18 /mL
—

Type

RX
RX

Active ingredient

METHADONE HYDROCHLORIDE
LEVOMETHADYL ACETATE HYDROCHLORIDE

Manufacturer

Hikma
Roxane

Dosage forms

Injectable, Solution, Tablet
—

Drug class

Opioid Agonist
—

Boxed warning

Boxed warning
None

Half-life

about 8 to 59 hours (terminal/elimination half-life; a very wide range)
—

Treats

Opioid-Related Disorders, Intractable Pain
Opioid-Related Disorders

Frequently asked questions

Which is better-rated, Methadone Hydrochloride or Orlaam?

By our independent rating, Methadone Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Orlaam. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Methadone Hydrochloride and Orlaam?

Methadone Hydrochloride contains Methadone Hydrochloride, while Orlaam contains Levomethadyl Acetate Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.