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METAXALONE vs ROBAXIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. METAXALONE and ROBAXIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

metaxalonerobaxin

Rating

70/100
72/100

Pharmacy pays

~$11.97 /30
~$1.27 /30

Type

RX
RX

Active ingredient

METAXALONE
METHOCARBAMOL

Manufacturer

Lannett Co Inc
Hikma

Dosage forms

Tablet
Injectable

Drug class

Muscle Relaxant
Muscle Relaxant

Boxed warning

None
None

Half-life

about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)
about 1 to 2 hours

Treats

Muscle Cramp, Muscle Rigidity, Muscle Spasticity
Muscle Cramp, Muscle Rigidity, Myositis

Frequently asked questions

Which is better-rated, Metaxalone or Robaxin?

By our independent rating, Robaxin scores higher — 3.6 vs 3.5 out of 5 for Metaxalone. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Metaxalone or Robaxin?

Robaxin costs pharmacies less to acquire — about $1.27 vs $11.97 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Metaxalone and Robaxin?

Metaxalone contains Metaxalone, while Robaxin contains Methocarbamol — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.