METAXALONE vs PRO-BANTHINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 5, 2026·How we rate

Possible drug interaction. METAXALONE and PRO-BANTHINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	METAXALONE	PRO-BANTHINE
Rating	72/100	72/100
Pharmacy pays	~$12.05 /30	—
Type	RX	RX
Active ingredient	METAXALONE	PROPANTHELINE BROMIDE
Manufacturer	Lannett Co Inc	Shire
Dosage forms	Tablet	Tablet, Injectable
Drug class	Muscle Relaxant	—
Boxed warning	None	None
Half-life	about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)	—
Treats	Muscle Cramp, Muscle Rigidity, Muscle Spasticity	Urinary Bladder Diseases, Pancreatitis, Peptic Ulcer

metaxalone pro-banthine

Rating

72/100

Pharmacy pays

~$12.05 /30

—

Type

Active ingredient

METAXALONE

PROPANTHELINE BROMIDE

Manufacturer

Lannett Co Inc

Shire

Dosage forms

Tablet

Tablet, Injectable

Drug class

Muscle Relaxant

—

Boxed warning

None

Half-life

about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)

—

Treats

Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Urinary Bladder Diseases, Pancreatitis, Peptic Ulcer

Frequently asked questions

Which is better-rated, Metaxalone or Pro-Banthine?

Metaxalone and Pro-Banthine are tied at 3.6 out of 5 by our independent rating.

What is the difference between Metaxalone and Pro-Banthine?

Metaxalone contains Metaxalone, while Pro-Banthine contains Propantheline Bromide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.