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METAXALONE vs PARAFON FORTE DSC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. METAXALONE and PARAFON FORTE DSC are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

~$11.87 /30
~$16.14 /30

Type

RX
RX

Active ingredient

METAXALONE
CHLORZOXAZONE

Dosage forms

Tablet
Tablet

Drug class

Muscle Relaxant
Muscle Relaxant

Boxed warning

None
None

Half-life

about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)

Treats

Muscle Cramp, Muscle Rigidity, Muscle Spasticity
Muscle Cramp, Muscle Rigidity, Myositis

Frequently asked questions

Which is cheaper, Metaxalone or Parafon Forte Dsc?

Metaxalone costs pharmacies less to acquire — about $11.87 vs $16.14 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Metaxalone and Parafon Forte Dsc?

Metaxalone contains Metaxalone, while Parafon Forte Dsc contains Chlorzoxazone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.