METAXALONE vs NORFLEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. METAXALONE and NORFLEX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	METAXALONE	NORFLEX
Rating	70/100	New
Pharmacy pays	~$11.97 /30	$0.48 /mL
Type	RX	RX
Active ingredient	METAXALONE	ORPHENADRINE CITRATE
Manufacturer	Lannett Co Inc	Bausch
Dosage forms	Tablet	Tablet, extended release, Injectable
Drug class	Muscle Relaxant	Muscle Relaxant
Boxed warning	None	None
Half-life	about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)	—
Treats	Muscle Cramp, Muscle Rigidity, Muscle Spasticity	Muscle Cramp, Muscle Rigidity, Myositis

metaxalone norflex

Rating

70/100

New

Pharmacy pays

~$11.97 /30

$0.48 /mL

Type

Active ingredient

METAXALONE

ORPHENADRINE CITRATE

Manufacturer

Lannett Co Inc

Bausch

Dosage forms

Tablet

Tablet, extended release, Injectable

Drug class

Muscle Relaxant

Boxed warning

None

Half-life

about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)

—

Treats

Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Muscle Cramp, Muscle Rigidity, Myositis

Frequently asked questions

What is the difference between Metaxalone and Norflex?

Metaxalone contains Metaxalone, while Norflex contains Orphenadrine Citrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.