MEPERGAN vs MYSOLINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. MEPERGAN and MYSOLINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MEPERGAN	MYSOLINE
Rating	72/100	74/100
Pharmacy pays	$0.16 /mL	~$2.89 /30
Type	RX	RX
Active ingredient	MEPERIDINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE	PRIMIDONE
Manufacturer	Hikma	Valeant Pharm Intl
Dosage forms	Injectable	Tablet
Drug class	—	Anti-Epileptic Agent
Boxed warning	None	None
Half-life	about 9 to 16 hours	—
Treats	—	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

mepergan mysoline

Rating

72/100

74/100

Pharmacy pays

$0.16 /mL

~$2.89 /30

Type

Active ingredient

MEPERIDINE HYDROCHLORIDE AND PROMETHAZINE HYDROCHLORIDE

PRIMIDONE

Manufacturer

Hikma

Valeant Pharm Intl

Dosage forms

Injectable

Tablet

Drug class

—

Anti-Epileptic Agent

Boxed warning

None

Half-life

about 9 to 16 hours

—

Treats

—

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

Frequently asked questions

Which is better-rated, Mepergan or Mysoline?

By our independent rating, Mysoline scores higher — 3.7 vs 3.6 out of 5 for Mepergan. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Mepergan and Mysoline?

Mepergan contains Meperidine Hydrochloride and Promethazine Hydrochloride, while Mysoline contains Primidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.