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MELLARIL-S vs STELAZINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. MELLARIL-S and STELAZINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

mellaril-sstelazine

Rating

70/100
70/100

Pharmacy pays

~$22.23 /30
~$22.02 /30

Type

RX
RX

Active ingredient

THIORIDAZINE
TRIFLUOPERAZINE HYDROCHLORIDE

Manufacturer

Novartis
Glaxosmithkline

Dosage forms

Suspension
Tablet

Drug class

Phenothiazine
Phenothiazine

Boxed warning

None
None

Treats

Psychotic Disorders, Schizophrenia
Anxiety Disorders, Psychotic Disorders, Schizophrenia

Frequently asked questions

Which is better-rated, Mellaril-S or Stelazine?

Mellaril-S and Stelazine are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Mellaril-S or Stelazine?

Stelazine costs pharmacies less to acquire — about $22.02 vs $22.23 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Mellaril-S and Stelazine?

Mellaril-S contains Thioridazine, while Stelazine contains Trifluoperazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.