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MEFLOQUINE HYDROCHLORIDE vs SOVUNA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Possible drug interaction. MEFLOQUINE HYDROCHLORIDE and SOVUNA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

~$127.75 /30
~$4.86 /30

Type

RX
RX

Active ingredient

MEFLOQUINE HYDROCHLORIDE
HYDROXYCHLOROQUINE SULFATE

Dosage forms

Tablet
Tablet

Drug class

Antimalarial
Antimalarial

Boxed warning

None
None

Half-life

about 40 to 50 days (terminal elimination half-life in whole blood)

Treats

Falciparum Malaria, Vivax Malaria
Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria

Frequently asked questions

Which is better-rated, Mefloquine Hydrochloride or Sovuna?

By our independent rating, Mefloquine Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Sovuna. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Mefloquine Hydrochloride or Sovuna?

Sovuna costs pharmacies less to acquire — about $4.86 vs $127.75 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Mefloquine Hydrochloride and Sovuna?

Mefloquine Hydrochloride contains Mefloquine Hydrochloride, while Sovuna contains Hydroxychloroquine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.