MATULANE vs OPDIVO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. MATULANE and OPDIVO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MATULANE	OPDIVO
Rating	New	72/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PROCARBAZINE HYDROCHLORIDE	NIVOLUMAB
Manufacturer	Leadiant Biosci Inc	Bristol Myers Squibb
Dosage forms	Capsule	Injectable
Drug class	—	Programmed Death Receptor-1 Blocking Antibody
Boxed warning	Boxed warning	None
Treats	Brain Neoplasms, Hodgkin Disease, Lung Neoplasms	Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

matulane opdivo

Rating

New

72/100

Pharmacy pays

—

Type

Active ingredient

PROCARBAZINE HYDROCHLORIDE

NIVOLUMAB

Manufacturer

Leadiant Biosci Inc

Bristol Myers Squibb

Dosage forms

Capsule

Injectable

Drug class

—

Programmed Death Receptor-1 Blocking Antibody

Boxed warning

None

Treats

Brain Neoplasms, Hodgkin Disease, Lung Neoplasms

Urinary Bladder Neoplasms, Non-Small-Cell Lung Carcinoma, Squamous Cell Carcinoma

Frequently asked questions

What is the difference between Matulane and Opdivo?

Matulane contains Procarbazine Hydrochloride, while Opdivo contains Nivolumab — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.