MAREZINE vs PROMETHEGAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. MAREZINE and PROMETHEGAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MAREZINE	PROMETHEGAN
Rating	70/100	70/100
Pharmacy pays	—	~$1.53 /30
Type	RX	RX
Active ingredient	CYCLIZINE LACTATE	PROMETHAZINE HYDROCHLORIDE
Manufacturer	Glaxosmithkline	Cosette
Dosage forms	Injectable	Suppository
Drug class	—	Phenothiazine
Boxed warning	None	Boxed warning
Half-life	—	about 9 to 16 hours
Treats	Dizziness, Nausea, Vertigo	Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

marezine promethegan

Rating

70/100

Pharmacy pays

—

~$1.53 /30

Type

Active ingredient

CYCLIZINE LACTATE

PROMETHAZINE HYDROCHLORIDE

Manufacturer

Glaxosmithkline

Cosette

Dosage forms

Injectable

Suppository

Drug class

—

Phenothiazine

Boxed warning

None

Boxed warning

Half-life

—

about 9 to 16 hours

Treats

Dizziness, Nausea, Vertigo

Anaphylaxis, Allergic Conjunctivitis, Motion Sickness

Frequently asked questions

Which is better-rated, Marezine or Promethegan?

Marezine and Promethegan are tied at 3.5 out of 5 by our independent rating.

What is the difference between Marezine and Promethegan?

Marezine contains Cyclizine Lactate, while Promethegan contains Promethazine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.