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MARCAINE vs XARACOLL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Rating

60/100
New

Pharmacy pays

$0.06 /mL
$0.06 /mL

Type

RX
RX

Active ingredient

BUPIVACAINE HYDROCHLORIDE
BUPIVACAINE HYDROCHLORIDE

Manufacturer

Dosage forms

Injectable
Implant

Drug class

Amide Local Anesthetic
Amide Local Anesthetic

Boxed warning

None
None

Treats

Postoperative Pain
Postoperative Pain

Frequently asked questions

Which is cheaper, Marcaine or Xaracoll?

Pharmacies pay about the same to acquire either one — roughly $0.06 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Marcaine and Xaracoll?

Both Marcaine and Xaracoll share the active ingredient Bupivacaine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.