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MARCAINE HYDROCHLORIDE PRESERVATIVE FREE vs MARCAINE HYDROCHLORIDE W/ EPINEPHRINE PRESERVATIVE FREE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Rating

40/100
40/100

Pharmacy pays

$0.06 /mL
$0.06 /mL

Type

RX
RX

Active ingredient

BUPIVACAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE
BUPIVACAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE

Manufacturer

Dosage forms

Injectable
Injectable

Drug class

—
—

Boxed warning

None
None

Frequently asked questions

Which is better-rated, Marcaine Hydrochloride Preservative Free or Marcaine Hydrochloride W/ Epinephrine Preservative Free?

Marcaine Hydrochloride Preservative Free and Marcaine Hydrochloride W/ Epinephrine Preservative Free are tied at 2.0 out of 5 by our independent rating.

Which is cheaper, Marcaine Hydrochloride Preservative Free or Marcaine Hydrochloride W/ Epinephrine Preservative Free?

Pharmacies pay about the same to acquire either one — roughly $0.06 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Marcaine Hydrochloride Preservative Free and Marcaine Hydrochloride W/ Epinephrine Preservative Free?

Both Marcaine Hydrochloride Preservative Free and Marcaine Hydrochloride W/ Epinephrine Preservative Free share the active ingredient Bupivacaine Hydrochloride and Epinephrine Bitartrate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.