MACRODANTIN vs MYSOLINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. MACRODANTIN and MYSOLINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	MACRODANTIN	MYSOLINE
Rating	New	74/100
Pharmacy pays	—	~$2.89 /30
Type	RX	RX
Active ingredient	NITROFURANTOIN, MACROCRYSTALLINE	PRIMIDONE
Manufacturer	Almatica	Valeant Pharm Intl
Dosage forms	Capsule	Tablet
Drug class	—	Anti-Epileptic Agent
Boxed warning	None	None
Half-life	about 20 minutes (roughly 0.3 hours) for the parent drug in adults with normal kidney function	—
Treats	—	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

macrodantin mysoline

Rating

New

74/100

Pharmacy pays

—

~$2.89 /30

Type

Active ingredient

NITROFURANTOIN, MACROCRYSTALLINE

PRIMIDONE

Manufacturer

Almatica

Valeant Pharm Intl

Dosage forms

Capsule

Tablet

Drug class

—

Anti-Epileptic Agent

Boxed warning

None

Half-life

about 20 minutes (roughly 0.3 hours) for the parent drug in adults with normal kidney function

—

Treats

—

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

Frequently asked questions

What is the difference between Macrodantin and Mysoline?

Macrodantin contains Nitrofurantoin, Macrocrystalline, while Mysoline contains Primidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.