LYBREL vs NORDETTE-21

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	LYBREL	NORDETTE-21
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	ETHINYL ESTRADIOL AND LEVONORGESTREL	ETHINYL ESTRADIOL AND LEVONORGESTREL
Manufacturer	Wyeth Pharms Inc	Teva Branded Pharm
Dosage forms	Tablet	Tablet
Drug class	—	—
Boxed warning	None	None
Half-life	about 36 hours (36 ± 13 hours at steady state)	about 36 hours (36 ± 13 hours at steady state)

lybrel nordette-21

Rating

New

Pharmacy pays

—

Type

Active ingredient

ETHINYL ESTRADIOL AND LEVONORGESTREL

Manufacturer

Wyeth Pharms Inc

Teva Branded Pharm

Dosage forms

Tablet

Drug class

—

Boxed warning

None

Half-life

about 36 hours (36 ± 13 hours at steady state)

Frequently asked questions

What is the difference between Lybrel and Nordette-21?

Both Lybrel and Nordette-21 share the active ingredient Ethinyl Estradiol and Levonorgestrel.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.