LURASIDONE HYDROCHLORIDE vs RYKINDO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 30, 2026·How we rate

Possible drug interaction. LURASIDONE HYDROCHLORIDE and RYKINDO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LURASIDONE HYDROCHLORIDE	RYKINDO
Rating	New	New
Pharmacy pays	~$9.42 /30	~$2.07 /30
Type	RX	RX
Active ingredient	LURASIDONE HYDROCHLORIDE	RISPERIDONE
Manufacturer	Chartwell Rx	Shandong Luye
Dosage forms	Tablet	Kit
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	Boxed warning	Boxed warning
Half-life	about 18 hours (mean, %CV 7), measured after a 40 mg oral dose in adults	about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)
Treats	Bipolar Disorder, Major Depressive Disorder, Schizophrenia	Autistic Disorder, Bipolar Disorder, Dementia

lurasidone hydrochloride rykindo

Rating

New

Pharmacy pays

~$9.42 /30

~$2.07 /30

Type

Active ingredient

LURASIDONE HYDROCHLORIDE

RISPERIDONE

Manufacturer

Chartwell Rx

Shandong Luye

Dosage forms

Tablet

Kit

Drug class

Atypical Antipsychotic

Boxed warning

Half-life

about 18 hours (mean, %CV 7), measured after a 40 mg oral dose in adults

about 3 hours in extensive CYP2D6 metabolizers (about 20 hours in poor metabolizers)

Treats

Bipolar Disorder, Major Depressive Disorder, Schizophrenia

Autistic Disorder, Bipolar Disorder, Dementia

Frequently asked questions

Which is cheaper, Lurasidone Hydrochloride or Rykindo?

Rykindo costs pharmacies less to acquire — about $2.07 vs $9.42 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Lurasidone Hydrochloride and Rykindo?

Lurasidone Hydrochloride contains Lurasidone Hydrochloride, while Rykindo contains Risperidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.