LURASIDONE HYDROCHLORIDE vs REXULTI

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. LURASIDONE HYDROCHLORIDE and REXULTI are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LURASIDONE HYDROCHLORIDE	REXULTI
Rating	New	New
Pharmacy pays	~$9.42 /30	—
Type	RX	RX
Active ingredient	LURASIDONE HYDROCHLORIDE	BREXPIPRAZOLE
Manufacturer	Chartwell Rx	Otsuka
Dosage forms	Tablet	Tablet, Kit
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	Boxed warning	Boxed warning
Half-life	about 18 hours (mean, %CV 7), measured after a 40 mg oral dose in adults	—
Treats	Bipolar Disorder, Major Depressive Disorder, Schizophrenia	Major Depressive Disorder, Schizophrenia

lurasidone hydrochloride rexulti

Rating

New

Pharmacy pays

~$9.42 /30

—

Type

Active ingredient

LURASIDONE HYDROCHLORIDE

BREXPIPRAZOLE

Manufacturer

Chartwell Rx

Otsuka

Dosage forms

Tablet

Tablet, Kit

Drug class

Atypical Antipsychotic

Boxed warning

Half-life

about 18 hours (mean, %CV 7), measured after a 40 mg oral dose in adults

—

Treats

Bipolar Disorder, Major Depressive Disorder, Schizophrenia

Major Depressive Disorder, Schizophrenia

Frequently asked questions

What is the difference between Lurasidone Hydrochloride and Rexulti?

Lurasidone Hydrochloride contains Lurasidone Hydrochloride, while Rexulti contains Brexpiprazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.