LUPRON DEPOT-PED KIT vs SYNAREL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. LUPRON DEPOT-PED KIT and SYNAREL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LUPRON DEPOT-PED KIT	SYNAREL
Rating	New	64/100
Pharmacy pays	~$6171.24 /30	—
Type	RX	RX
Active ingredient	LEUPROLIDE ACETATE	NAFARELIN ACETATE
Manufacturer	Abbvie Endocrine Inc	Pfizer
Dosage forms	Kit	Spray/Inhaler, metered
Drug class	Gonadotropin Releasing Hormone Receptor Agonist	—
Boxed warning	None	None
Treats	Breast Neoplasms, Endometriosis, Infertility	Endometriosis, Precocious Puberty

lupron depot-ped kit synarel

Rating

New

64/100

Pharmacy pays

~$6171.24 /30

—

Type

Active ingredient

LEUPROLIDE ACETATE

NAFARELIN ACETATE

Manufacturer

Abbvie Endocrine Inc

Pfizer

Dosage forms

Kit

Spray/Inhaler, metered

Drug class

Gonadotropin Releasing Hormone Receptor Agonist

—

Boxed warning

None

Treats

Breast Neoplasms, Endometriosis, Infertility

Endometriosis, Precocious Puberty

Frequently asked questions

What is the difference between Lupron Depot-Ped Kit and Synarel?

Lupron Depot-Ped Kit contains Leuprolide Acetate, while Synarel contains Nafarelin Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.