LUPKYNIS vs NEORAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. LUPKYNIS and NEORAL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LUPKYNIS	NEORAL
Rating	New	70/100
Pharmacy pays	—	~$52.85 /30
Type	RX	RX
Active ingredient	VOCLOSPORIN	CYCLOSPORINE
Manufacturer	Aurinia	Novartis
Dosage forms	Capsule	Capsule, Solution
Drug class	Calcineurin Inhibitor Immunosuppressant	Calcineurin Inhibitor Immunosuppressant
Boxed warning	None	Boxed warning
Half-life	—	about 8.4 hours (range 5 to 18 hours)
Treats	Lupus Nephritis	Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus

lupkynis neoral

Rating

New

70/100

Pharmacy pays

—

~$52.85 /30

Type

Active ingredient

VOCLOSPORIN

CYCLOSPORINE

Manufacturer

Aurinia

Novartis

Dosage forms

Capsule

Capsule, Solution

Drug class

Calcineurin Inhibitor Immunosuppressant

Boxed warning

None

Boxed warning

Half-life

—

about 8.4 hours (range 5 to 18 hours)

Treats

Lupus Nephritis

Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus

Frequently asked questions

What is the difference between Lupkynis and Neoral?

Lupkynis contains Voclosporin, while Neoral contains Cyclosporine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.