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LUMAKRAS vs ROZLYTREK

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. LUMAKRAS and ROZLYTREK are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

lumakrasrozlytrek

Rating

72/100
70/100

Pharmacy pays

—
—

Type

RX
RX

Active ingredient

SOTORASIB
ENTRECTINIB

Manufacturer

Amgen Inc
Genentech Inc

Dosage forms

Tablet
Capsule, Oral pellets

Drug class

—
—

Boxed warning

None
None

Treats

Non-Small-Cell Lung Carcinoma
Non-Small-Cell Lung Carcinoma

Frequently asked questions

Which is better-rated, Lumakras or Rozlytrek?

By our independent rating, Lumakras scores higher — 3.6 vs 3.5 out of 5 for Rozlytrek. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Lumakras and Rozlytrek?

Lumakras contains Sotorasib, while Rozlytrek contains Entrectinib — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.