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LUMAKRAS vs PORTRAZZA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 13, 2026·How we rate

Possible drug interaction. LUMAKRAS and PORTRAZZA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

Type

RX
RX

Active ingredient

SOTORASIB
NECITUMUMAB

Dosage forms

Tablet
Injectable

Drug class

Boxed warning

None
None

Treats

Non-Small-Cell Lung Carcinoma
Non-Small-Cell Lung Carcinoma

Frequently asked questions

Which is better-rated, Lumakras or Portrazza?

By our independent rating, Lumakras scores higher — 3.6 vs 3.5 out of 5 for Portrazza. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Lumakras and Portrazza?

Lumakras contains Sotorasib, while Portrazza contains Necitumumab — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.