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LOZOL vs METOLAZONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. LOZOL and METOLAZONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
72/100

Pharmacy pays

~$3.28 /30
~$8.76 /30

Type

RX
RX

Active ingredient

INDAPAMIDE
METOLAZONE

Dosage forms

Tablet
Tablet

Drug class

Thiazide-Like Diuretic
Thiazide-Like Diuretic

Boxed warning

None
None

Treats

Edema, Heart Failure, Hypertension
Edema, Heart Failure, Hypertension

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Frequently asked questions

Which is better-rated, Lozol or Metolazone?

By our independent rating, Metolazone scores higher — 3.6 vs 3.5 out of 5 for Lozol. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Lozol or Metolazone?

Lozol costs pharmacies less to acquire — about $3.28 vs $8.76 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Lozol and Metolazone?

Lozol contains Indapamide, while Metolazone contains Metolazone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.