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LOTRIMIN vs SPECTAZOLE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. LOTRIMIN and SPECTAZOLE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

$0.21 /mL
$0.36 /g

Type

RX
RX

Active ingredient

CLOTRIMAZOLE
ECONAZOLE NITRATE

Dosage forms

Topical
Topical

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Treats

Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis
Cutaneous Candidiasis, Tinea Pedis, Tinea Versicolor

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Frequently asked questions

What is the difference between Lotrimin and Spectazole?

Lotrimin contains Clotrimazole, while Spectazole contains Econazole Nitrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.