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LOTRIMIN AF vs NIZORAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Rating

New
70/100

Pharmacy pays

$0.21 /mL
$0.27 /g

Type

OTC
RX

Active ingredient

CLOTRIMAZOLE
KETOCONAZOLE

Dosage forms

Spray/Inhaler
Topical

Drug class

Azole Antifungal
Azole Antifungal

Boxed warning

None
None

Treats

Cutaneous Candidiasis, Oral Candidiasis, Vulvovaginal Candidiasis
Blastomycosis, Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis

Get nizoralhigher-rated option

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Frequently asked questions

What is the difference between Lotrimin Af and Nizoral?

Lotrimin Af contains Clotrimazole, while Nizoral contains Ketoconazole — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.