LOREEV XR vs SYMPAZAN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. LOREEV XR and SYMPAZAN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LOREEV XR	SYMPAZAN
Rating	New	New
Pharmacy pays	~$1.14 /30	~$7.72 /30
Type	RX	RX
Active ingredient	LORAZEPAM	CLOBAZAM
Manufacturer	Almatica	Assertio Speclty
Dosage forms	Capsule, extended release	Film
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	Boxed warning	Boxed warning
Half-life	about 12 hours (mean)	—
Treats	Anxiety Disorders, Catatonia, Depressive Disorder	Seizures, Lennox Gastaut Syndrome

loreev xr sympazan

Rating

New

Pharmacy pays

~$1.14 /30

~$7.72 /30

Type

Active ingredient

LORAZEPAM

CLOBAZAM

Manufacturer

Almatica

Assertio Speclty

Dosage forms

Capsule, extended release

Film

Drug class

Benzodiazepine

Boxed warning

Half-life

about 12 hours (mean)

—

Treats

Anxiety Disorders, Catatonia, Depressive Disorder

Seizures, Lennox Gastaut Syndrome

Frequently asked questions

Which is cheaper, Loreev XR or Sympazan?

Loreev XR costs pharmacies less to acquire — about $1.14 vs $7.72 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Loreev XR and Sympazan?

Loreev XR contains Lorazepam, while Sympazan contains Clobazam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.