LOREEV XR vs LYGEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. LOREEV XR and LYGEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LOREEV XR	LYGEN
Rating	New	New
Pharmacy pays	~$1.14 /30	~$4.83 /30
Type	RX	RX
Active ingredient	LORAZEPAM	CHLORDIAZEPOXIDE HYDROCHLORIDE
Manufacturer	Almatica	Alra
Dosage forms	Capsule, extended release	Capsule
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	Boxed warning	None
Half-life	about 12 hours (mean)	—
Treats	Anxiety Disorders, Catatonia, Depressive Disorder	Alcohol Withdrawal Delirium, Anxiety Disorders

loreev xr lygen

Rating

New

Pharmacy pays

~$1.14 /30

~$4.83 /30

Type

Active ingredient

LORAZEPAM

CHLORDIAZEPOXIDE HYDROCHLORIDE

Manufacturer

Almatica

Alra

Dosage forms

Capsule, extended release

Capsule

Drug class

Benzodiazepine

Boxed warning

None

Half-life

about 12 hours (mean)

—

Treats

Anxiety Disorders, Catatonia, Depressive Disorder

Alcohol Withdrawal Delirium, Anxiety Disorders

Frequently asked questions

Which is cheaper, Loreev XR or Lygen?

Loreev XR costs pharmacies less to acquire — about $1.14 vs $4.83 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Loreev XR and Lygen?

Loreev XR contains Lorazepam, while Lygen contains Chlordiazepoxide Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.