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LORAZEPAM vs SONATA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 5, 2026·How we rate

Possible drug interaction. LORAZEPAM and SONATA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
60/100

Pharmacy pays

~$1.14 /30
~$4.54 /30

Type

RX
RX

Active ingredient

LORAZEPAM
ZALEPLON

Manufacturer

Dosage forms

Injectable, Solution, Liquid, Tablet
Capsule

Drug class

Benzodiazepine
Gamma-Aminobutyric Acid A Receptor Agonist

Boxed warning

Half-life

about 12 hours (mean)
—

Treats

Anxiety Disorders, Catatonia, Depressive Disorder
Sleep Initiation and Maintenance Disorders

Frequently asked questions

Which is better-rated, Lorazepam or Sonata?

By our independent rating, Lorazepam scores higher — 3.6 vs 3.0 out of 5 for Sonata. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Lorazepam or Sonata?

Lorazepam costs pharmacies less to acquire — about $1.14 vs $4.54 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Lorazepam and Sonata?

Lorazepam contains Lorazepam, while Sonata contains Zaleplon — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.