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LOPERAMIDE HYDROCHLORIDE vs WESTADONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. LOPERAMIDE HYDROCHLORIDE and WESTADONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
68/100

Pharmacy pays

$0.05 /mL
$0.18 /mL

Type

RX
RX

Active ingredient

LOPERAMIDE HYDROCHLORIDE
METHADONE HYDROCHLORIDE

Dosage forms

Capsule
Tablet, effervescent

Drug class

Opioid Agonist
Opioid Agonist

Boxed warning

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)
about 8 to 59 hours (terminal/elimination half-life; a very wide range)

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery
Opioid-Related Disorders, Intractable Pain

Frequently asked questions

Which is better-rated, Loperamide Hydrochloride or Westadone?

By our independent rating, Loperamide Hydrochloride scores higher — 3.5 vs 3.4 out of 5 for Westadone. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Loperamide Hydrochloride or Westadone?

Loperamide Hydrochloride costs pharmacies less to acquire — about $0.05 vs $0.18 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Loperamide Hydrochloride and Westadone?

Loperamide Hydrochloride contains Loperamide Hydrochloride, while Westadone contains Methadone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.