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LOPERAMIDE HYDROCHLORIDE vs OXAYDO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. LOPERAMIDE HYDROCHLORIDE and OXAYDO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

$0.05 /mL
$0.08 /mL

Type

RX
RX

Active ingredient

LOPERAMIDE HYDROCHLORIDE
OXYCODONE HYDROCHLORIDE

Dosage forms

Capsule
Tablet

Drug class

Opioid Agonist
Opioid Agonist

Half-life

about 10.8 hours (range 9.1 to 14.4 hours)
about 3.5 to 4 hours

Treats

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery
Postoperative Pain

Frequently asked questions

Which is cheaper, Loperamide Hydrochloride or Oxaydo?

Loperamide Hydrochloride costs pharmacies less to acquire — about $0.05 vs $0.08 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Loperamide Hydrochloride and Oxaydo?

Loperamide Hydrochloride contains Loperamide Hydrochloride, while Oxaydo contains Oxycodone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.