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LONSURF vs MYSOLINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated September 26, 2026·How we rate

Possible drug interaction. LONSURF and MYSOLINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
74/100

Pharmacy pays

—
~$2.89 /30

Type

RX
RX

Active ingredient

TIPIRACIL HYDROCHLORIDE AND TRIFLURIDINE
PRIMIDONE

Dosage forms

Tablet
Tablet

Drug class

—
Anti-Epileptic Agent

Boxed warning

None
None

Treats

—
Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

Frequently asked questions

What is the difference between Lonsurf and Mysoline?

Lonsurf contains Tipiracil Hydrochloride and Trifluridine, while Mysoline contains Primidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.