LOMUSTINE vs MELPHALAN HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. LOMUSTINE and MELPHALAN HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LOMUSTINE	MELPHALAN HYDROCHLORIDE
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	LOMUSTINE	MELPHALAN HYDROCHLORIDE
Manufacturer	Carnegie	Arthur Grp
Dosage forms	Capsule	Kit
Drug class	Alkylating Drug	Alkylating Drug
Boxed warning	Boxed warning	Boxed warning
Half-life	about 16 to 48 hours — but note this is the half-life of lomustine's metabolites, not the parent drug	—
Treats	Brain Neoplasms, Colonic Neoplasms, Hodgkin Disease	Breast Neoplasms, Multiple Myeloma, Neuroblastoma

lomustine melphalan hydrochloride

Rating

New

Pharmacy pays

—

Type

Active ingredient

LOMUSTINE

MELPHALAN HYDROCHLORIDE

Manufacturer

Carnegie

Arthur Grp

Dosage forms

Capsule

Kit

Drug class

Alkylating Drug

Boxed warning

Half-life

about 16 to 48 hours — but note this is the half-life of lomustine's metabolites, not the parent drug

—

Treats

Brain Neoplasms, Colonic Neoplasms, Hodgkin Disease

Breast Neoplasms, Multiple Myeloma, Neuroblastoma

Frequently asked questions

What is the difference between Lomustine and Melphalan Hydrochloride?

Lomustine contains Lomustine, while Melphalan Hydrochloride contains Melphalan Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.