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LO-TROL vs LOMOTIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Rating

New
52/100

Pharmacy pays

$6.87 /mL
$6.87 /mL

Type

RX
RX

Active ingredient

ATROPINE SULFATE AND DIPHENOXYLATE HYDROCHLORIDE
ATROPINE SULFATE AND DIPHENOXYLATE HYDROCHLORIDE

Manufacturer

Dosage forms

Tablet
Tablet

Drug class

—
—

Boxed warning

None
None

Frequently asked questions

Which is cheaper, Lo-Trol or Lomotil?

Pharmacies pay about the same to acquire either one — roughly $6.87 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Lo-Trol and Lomotil?

Both Lo-Trol and Lomotil share the active ingredient Atropine Sulfate and Diphenoxylate Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.