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LOESTRIN FE 1/20 vs NORLESTRIN 21 2.5/50

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Rating

New
New

Pharmacy pays

Type

RX
RX

Active ingredient

ETHINYL ESTRADIOL AND NORETHINDRONE ACETATE
ETHINYL ESTRADIOL AND NORETHINDRONE ACETATE

Dosage forms

Tablet
Tablet

Drug class

Boxed warning

None
None

Half-life

about 8 hours
about 8 hours

Frequently asked questions

What is the difference between Loestrin Fe 1/20 and Norlestrin 21 2.5/50?

Both Loestrin Fe 1/20 and Norlestrin 21 2.5/50 share the active ingredient Ethinyl Estradiol and Norethindrone Acetate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.