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LO-TROL vs LOMOTIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Rating

New
58/100

Pharmacy pays

$6.87 /mL
$6.87 /mL

Type

RX
RX

Active ingredient

ATROPINE SULFATE AND DIPHENOXYLATE HYDROCHLORIDE
ATROPINE SULFATE AND DIPHENOXYLATE HYDROCHLORIDE

Manufacturer

Dosage forms

Tablet
Tablet

Drug class

Boxed warning

None
None

Frequently asked questions

Which is cheaper, Lo-Trol or Lomotil?

Pharmacies pay about the same to acquire either one — roughly $6.87 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Lo-Trol and Lomotil?

Both Lo-Trol and Lomotil share the active ingredient Atropine Sulfate and Diphenoxylate Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.