LINZESS vs ZELNORM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. LINZESS and ZELNORM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LINZESS	ZELNORM
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	LINACLOTIDE	TEGASEROD MALEATE
Manufacturer	Abbvie	Alfasigma
Dosage forms	Capsule	Tablet
Drug class	Guanylate Cyclase-C Agonist	—
Boxed warning	Boxed warning	None
Treats	Constipation, Irritable Bowel Syndrome	Constipation, Irritable Bowel Syndrome

linzess zelnorm

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

LINACLOTIDE

TEGASEROD MALEATE

Manufacturer

Abbvie

Alfasigma

Dosage forms

Capsule

Tablet

Drug class

Guanylate Cyclase-C Agonist

—

Boxed warning

None

Treats

Constipation, Irritable Bowel Syndrome

Frequently asked questions

What is the difference between Linzess and Zelnorm?

Linzess contains Linaclotide, while Zelnorm contains Tegaserod Maleate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.