LIDOCAINE HYDROCHLORIDE PRESERVATIVE FREE vs XYLOCAINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	LIDOCAINE HYDROCHLORIDE PRESERVATIVE FREE	XYLOCAINE
Rating	72/100	70/100
Pharmacy pays	$0.24 /mL	$0.24 /mL
Type	RX	RX
Active ingredient	LIDOCAINE HYDROCHLORIDE	LIDOCAINE HYDROCHLORIDE
Manufacturer	Hikma	Epic Pharma LLC
Dosage forms	Injectable	Injectable
Drug class	Amide Local Anesthetic	Amide Local Anesthetic
Boxed warning	None	None
Treats	Burns, Esophageal Diseases, Mouth Diseases	Burns, Esophageal Diseases, Mouth Diseases

lidocaine hydrochloride preservative free xylocaine

Rating

72/100

70/100

Pharmacy pays

$0.24 /mL

Type

Active ingredient

LIDOCAINE HYDROCHLORIDE

Manufacturer

Hikma

Epic Pharma LLC

Dosage forms

Injectable

Drug class

Amide Local Anesthetic

Boxed warning

None

Treats

Burns, Esophageal Diseases, Mouth Diseases

Frequently asked questions

Which is better-rated, Lidocaine Hydrochloride Preservative Free or Xylocaine?

By our independent rating, Lidocaine Hydrochloride Preservative Free scores higher — 3.6 vs 3.5 out of 5 for Xylocaine. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Lidocaine Hydrochloride Preservative Free or Xylocaine?

Pharmacies pay about the same to acquire either one — roughly $0.24 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Lidocaine Hydrochloride Preservative Free and Xylocaine?

Both Lidocaine Hydrochloride Preservative Free and Xylocaine share the active ingredient Lidocaine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.