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LICART vs RUFEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. LICART and RUFEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
70/100

Pharmacy pays

~$146.33 /30
$0.04 /mL

Type

RX
RX

Active ingredient

DICLOFENAC EPOLAMINE
IBUPROFEN

Manufacturer

Dosage forms

System
Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea
Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Frequently asked questions

What is the difference between Licart and Rufen?

Licart contains Diclofenac Epolamine, while Rufen contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.