LEVO-DROMORAN vs NUCYNTA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 14, 2026·How we rate

Possible drug interaction. LEVO-DROMORAN and NUCYNTA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LEVO-DROMORAN	NUCYNTA
Rating	70/100	New
Pharmacy pays	~$319.37 /30	~$342.56 /30
Type	RX	RX
Active ingredient	LEVORPHANOL TARTRATE	TAPENTADOL HYDROCHLORIDE
Manufacturer	Valeant Pharm Intl	Collegium Pharm Inc
Dosage forms	Injectable, Tablet	Tablet
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	—	about 5 hours (terminal half-life, on average, after oral administration)
Treats	Pain	Pain

levo-dromoran nucynta

Rating

70/100

New

Pharmacy pays

~$319.37 /30

~$342.56 /30

Type

Active ingredient

LEVORPHANOL TARTRATE

TAPENTADOL HYDROCHLORIDE

Manufacturer

Valeant Pharm Intl

Collegium Pharm Inc

Dosage forms

Injectable, Tablet

Tablet

Drug class

Opioid Agonist

Boxed warning

None

Half-life

—

about 5 hours (terminal half-life, on average, after oral administration)

Treats

Pain

Frequently asked questions

Which is cheaper, Levo-Dromoran or Nucynta?

Levo-Dromoran costs pharmacies less to acquire — about $319.37 vs $342.56 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Levo-Dromoran and Nucynta?

Levo-Dromoran contains Levorphanol Tartrate, while Nucynta contains Tapentadol Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.