LEUCOVORIN CALCIUM vs VYKOURA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	LEUCOVORIN CALCIUM	VYKOURA
Rating	New	New
Pharmacy pays	~$59.34 /30	~$59.34 /30
Type	RX	RX
Active ingredient	LEUCOVORIN CALCIUM	LEUCOVORIN CALCIUM
Manufacturer	Abic	Avyxa Holdings
Dosage forms	Injectable, Tablet	Injectable
Drug class	Folate Analog	Folate Analog
Boxed warning	None	None
Treats	Megaloblastic Anemia, Folic Acid Deficiency, Drug-Related Side Effects and Adverse Reactions	Megaloblastic Anemia, Folic Acid Deficiency, Drug-Related Side Effects and Adverse Reactions

leucovorin calcium vykoura

Rating

New

Pharmacy pays

~$59.34 /30

Type

Active ingredient

LEUCOVORIN CALCIUM

Manufacturer

Abic

Avyxa Holdings

Dosage forms

Injectable, Tablet

Injectable

Drug class

Folate Analog

Boxed warning

None

Treats

Megaloblastic Anemia, Folic Acid Deficiency, Drug-Related Side Effects and Adverse Reactions

Frequently asked questions

Which is cheaper, Leucovorin Calcium or Vykoura?

Pharmacies pay about the same to acquire either one — roughly $59.34 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Leucovorin Calcium and Vykoura?

Both Leucovorin Calcium and Vykoura share the active ingredient Leucovorin Calcium.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.