LETYBO vs METAXALONE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. LETYBO and METAXALONE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LETYBO	METAXALONE
Rating	New	70/100
Pharmacy pays	—	~$11.97 /30
Type	RX	RX
Active ingredient	LETIBOTULINUMTOXINA-WLBG	METAXALONE
Manufacturer	Hugel Inc	Lannett Co Inc
Dosage forms	Injectable	Tablet
Drug class	—	Muscle Relaxant
Boxed warning	Boxed warning	None
Half-life	—	about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)
Treats	Blepharospasm, Dystonia, Fissure in Ano	Muscle Cramp, Muscle Rigidity, Muscle Spasticity

letybo metaxalone

Rating

New

70/100

Pharmacy pays

—

~$11.97 /30

Type

Active ingredient

LETIBOTULINUMTOXINA-WLBG

METAXALONE

Manufacturer

Hugel Inc

Lannett Co Inc

Dosage forms

Injectable

Tablet

Drug class

—

Muscle Relaxant

Boxed warning

None

Half-life

—

about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)

Treats

Blepharospasm, Dystonia, Fissure in Ano

Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Frequently asked questions

What is the difference between Letybo and Metaxalone?

Letybo contains Letibotulinumtoxina-Wlbg, while Metaxalone contains Metaxalone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.