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LETAIRIS vs UPTRAVI

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. LETAIRIS and UPTRAVI are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

letairisuptravi

Rating

70/100
New

Pharmacy pays

~$255.61 /30
—

Type

RX
RX

Active ingredient

AMBRISENTAN
SELEXIPAG

Manufacturer

Gilead Sciences Inc
Actelion

Dosage forms

Tablet
Injectable, Tablet

Drug class

Endothelin Receptor Antagonist
—

Boxed warning

Boxed warning
None

Treats

Pulmonary Hypertension
Pulmonary Hypertension

Frequently asked questions

What is the difference between Letairis and Uptravi?

Letairis contains Ambrisentan, while Uptravi contains Selexipag — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.