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LESCOL XL vs ROSUVASTATIN CALCIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. LESCOL XL and ROSUVASTATIN CALCIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

68/100
64/100

Pharmacy pays

~$85.52 /30
~$1.37 /30

Type

RX
RX

Active ingredient

FLUVASTATIN SODIUM
ROSUVASTATIN CALCIUM

Manufacturer

Dosage forms

Tablet, extended release
Tablet

Drug class

Hmg-Coa Reductase Inhibitor
Hmg-Coa Reductase Inhibitor

Boxed warning

None
None

Half-life

about 19 hours

Treats

Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias
Coronary Artery Disease, Hypercholesterolemia, Hyperlipoproteinemias

Frequently asked questions

Which is better-rated, Lescol XL or Rosuvastatin Calcium?

By our independent rating, Lescol XL scores higher — 3.4 vs 3.2 out of 5 for Rosuvastatin Calcium. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Lescol XL or Rosuvastatin Calcium?

Rosuvastatin Calcium costs pharmacies less to acquire — about $1.37 vs $85.52 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Lescol XL and Rosuvastatin Calcium?

Lescol XL contains Fluvastatin Sodium, while Rosuvastatin Calcium contains Rosuvastatin Calcium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.