LEQSELVI vs OPZELURA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. LEQSELVI and OPZELURA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LEQSELVI	OPZELURA
Rating	New	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	DEURUXOLITINIB PHOSPHATE	RUXOLITINIB PHOSPHATE
Manufacturer	Sun Pharm Inds Inc	Incyte Corp
Dosage forms	Tablet	Topical
Drug class	Janus Kinase Inhibitor	Janus Kinase Inhibitor
Boxed warning	Boxed warning	Boxed warning
Treats	Alopecia Areata	Polycythemia Vera, Primary Myelofibrosis

leqselvi opzelura

Rating

New

Pharmacy pays

—

Type

Active ingredient

DEURUXOLITINIB PHOSPHATE

RUXOLITINIB PHOSPHATE

Manufacturer

Sun Pharm Inds Inc

Incyte Corp

Dosage forms

Tablet

Topical

Drug class

Janus Kinase Inhibitor

Boxed warning

Treats

Alopecia Areata

Polycythemia Vera, Primary Myelofibrosis

Frequently asked questions

What is the difference between Leqselvi and Opzelura?

Leqselvi contains Deuruxolitinib Phosphate, while Opzelura contains Ruxolitinib Phosphate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.