LAMICTAL vs SEZABY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. LAMICTAL and SEZABY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LAMICTAL	SEZABY
Rating	70/100	New
Pharmacy pays	~$4.39 /30	~$3.49 /30
Type	RX	RX
Active ingredient	LAMOTRIGINE	PHENOBARBITAL SODIUM
Manufacturer	Glaxosmithkline	Sun Pharm Inds Inc
Dosage forms	Tablet, Kit	Injectable
Drug class	Anti-Epileptic Agent	—
Boxed warning	Boxed warning	Boxed warning
Half-life	about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism	—
Treats	Bipolar Disorder, Partial Epilepsies, Seizures	Febrile Seizures, Partial Epilepsies, Tonic-Clonic Epilepsy

lamictal sezaby

Rating

70/100

New

Pharmacy pays

~$4.39 /30

~$3.49 /30

Type

Active ingredient

LAMOTRIGINE

PHENOBARBITAL SODIUM

Manufacturer

Glaxosmithkline

Sun Pharm Inds Inc

Dosage forms

Tablet, Kit

Injectable

Drug class

Anti-Epileptic Agent

—

Boxed warning

Half-life

about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism

—

Treats

Bipolar Disorder, Partial Epilepsies, Seizures

Febrile Seizures, Partial Epilepsies, Tonic-Clonic Epilepsy

Frequently asked questions

Which is cheaper, Lamictal or Sezaby?

Sezaby costs pharmacies less to acquire — about $3.49 vs $4.39 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Lamictal and Sezaby?

Lamictal contains Lamotrigine, while Sezaby contains Phenobarbital Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.