LAMICTAL ODT vs VIGAFYDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. LAMICTAL ODT and VIGAFYDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LAMICTAL ODT	VIGAFYDE
Rating	70/100	New
Pharmacy pays	~$4.39 /30	—
Type	RX	RX
Active ingredient	LAMOTRIGINE	VIGABATRIN
Manufacturer	Glaxosmithkline	Pyros Pharms
Dosage forms	Tablet, orally disintegrating, Kit	Solution
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	Boxed warning	Boxed warning
Half-life	about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism	—
Treats	Bipolar Disorder, Partial Epilepsies, Seizures	Infantile Spasms, Complex Partial Epilepsy

lamictal odt vigafyde

Rating

70/100

New

Pharmacy pays

~$4.39 /30

—

Type

Active ingredient

LAMOTRIGINE

VIGABATRIN

Manufacturer

Glaxosmithkline

Pyros Pharms

Dosage forms

Tablet, orally disintegrating, Kit

Solution

Drug class

Anti-Epileptic Agent

Boxed warning

Half-life

about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism

—

Treats

Bipolar Disorder, Partial Epilepsies, Seizures

Infantile Spasms, Complex Partial Epilepsy

Frequently asked questions

What is the difference between Lamictal ODT and Vigafyde?

Lamictal ODT contains Lamotrigine, while Vigafyde contains Vigabatrin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.