LAMICTAL CD vs VALPROATE SODIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. LAMICTAL CD and VALPROATE SODIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LAMICTAL CD	VALPROATE SODIUM
Rating	70/100	70/100
Pharmacy pays	~$4.39 /30	—
Type	RX	RX
Active ingredient	LAMOTRIGINE	VALPROATE SODIUM
Manufacturer	Glaxosmithkline	Sagent
Dosage forms	Tablet	Injectable, Solution
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	Boxed warning	Boxed warning
Half-life	about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism	about 9 to 16 hours (the label's mean terminal, or elimination, half-life for valproate monotherapy after oral doses of 250 to 1,000 mg)
Treats	Bipolar Disorder, Partial Epilepsies, Seizures	—

lamictal cd valproate sodium

Rating

70/100

Pharmacy pays

~$4.39 /30

—

Type

Active ingredient

LAMOTRIGINE

VALPROATE SODIUM

Manufacturer

Glaxosmithkline

Sagent

Dosage forms

Tablet

Injectable, Solution

Drug class

Anti-Epileptic Agent

Boxed warning

Half-life

about 25 to 33 hours in healthy adults taking no other medications — the label reports a mean elimination half-life of 32.8 hours after a single dose (individual range 14 to 103 hours) and 25.4 hours with repeat dosing (range 11.6 to 61.6 hours), since lamotrigine induces its own metabolism

about 9 to 16 hours (the label's mean terminal, or elimination, half-life for valproate monotherapy after oral doses of 250 to 1,000 mg)

Treats

Bipolar Disorder, Partial Epilepsies, Seizures

—

Frequently asked questions

Which is better-rated, Lamictal Cd or Valproate Sodium?

Lamictal Cd and Valproate Sodium are tied at 3.5 out of 5 by our independent rating.

What is the difference between Lamictal Cd and Valproate Sodium?

Lamictal Cd contains Lamotrigine, while Valproate Sodium contains Valproate Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.