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LACTULOSE vs TRULANCE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. LACTULOSE and TRULANCE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

lactulosetrulance

Rating

68/100
New

Pharmacy pays

~$0.73 /30
—

Type

RX
RX

Active ingredient

LACTULOSE
PLECANATIDE

Manufacturer

Fresenius Kabi USA
Salix

Dosage forms

Solution, Powder
Tablet

Drug class

Osmotic Laxative
—

Boxed warning

None
Boxed warning

Treats

Constipation, Hepatic Encephalopathy
Constipation

Frequently asked questions

What is the difference between Lactulose and Trulance?

Lactulose contains Lactulose, while Trulance contains Plecanatide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.