LACTULOSE vs MIRALAX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. LACTULOSE and MIRALAX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	LACTULOSE	MIRALAX
Rating	66/100	70/100
Pharmacy pays	~$0.72 /30	$1.11 /g
Type	RX	RX
Active ingredient	LACTULOSE	POLYETHYLENE GLYCOL 3350
Manufacturer	Fresenius Kabi USA	Braintree
Dosage forms	Solution, Powder	Powder
Drug class	Osmotic Laxative	Osmotic Laxative
Boxed warning	None	None
Treats	Constipation, Hepatic Encephalopathy	Constipation

lactulose miralax

Rating

66/100

70/100

Pharmacy pays

~$0.72 /30

$1.11 /g

Type

Active ingredient

LACTULOSE

POLYETHYLENE GLYCOL 3350

Manufacturer

Fresenius Kabi USA

Braintree

Dosage forms

Solution, Powder

Powder

Drug class

Osmotic Laxative

Boxed warning

None

Treats

Constipation, Hepatic Encephalopathy

Constipation

Frequently asked questions

Which is better-rated, Lactulose or Miralax?

By our independent rating, Miralax scores higher — 3.5 vs 3.3 out of 5 for Lactulose. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Lactulose and Miralax?

Lactulose contains Lactulose, while Miralax contains Polyethylene Glycol 3350 — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.