KYTRIL vs ZOFRAN ODT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. KYTRIL and ZOFRAN ODT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	KYTRIL	ZOFRAN ODT
Rating	New	68/100
Pharmacy pays	~$33.48 /30	$0.15 /mL
Type	RX	RX
Active ingredient	GRANISETRON HYDROCHLORIDE	ONDANSETRON
Manufacturer	Roche	Sandoz
Dosage forms	Injectable, Tablet	Tablet, orally disintegrating
Drug class	Serotonin-3 Receptor Antagonist	Serotonin-3 Receptor Antagonist
Boxed warning	None	None
Half-life	—	about 3 to 5 hours (roughly 4 hours) in healthy adults
Treats	—	Alcoholism

kytril zofran odt

Rating

New

68/100

Pharmacy pays

~$33.48 /30

$0.15 /mL

Type

Active ingredient

GRANISETRON HYDROCHLORIDE

ONDANSETRON

Manufacturer

Roche

Sandoz

Dosage forms

Injectable, Tablet

Tablet, orally disintegrating

Drug class

Serotonin-3 Receptor Antagonist

Boxed warning

None

Half-life

—

about 3 to 5 hours (roughly 4 hours) in healthy adults

Treats

—

Alcoholism

Frequently asked questions

What is the difference between Kytril and Zofran ODT?

Kytril contains Granisetron Hydrochloride, while Zofran ODT contains Ondansetron — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.