KEYTRUDA vs LENVIMA

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. KEYTRUDA and LENVIMA are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	KEYTRUDA	LENVIMA
Rating	72/100	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	PEMBROLIZUMAB	LENVATINIB MESYLATE
Manufacturer	Merck Sharp Dohme	Eisai Inc
Dosage forms	Injectable	Capsule, Kit
Drug class	Programmed Death Receptor-1 Blocking Antibody	—
Boxed warning	None	None
Treats	Malignant Mesothelioma, Biliary Tract Neoplasms, Urinary Bladder Neoplasms	Renal Cell Carcinoma, Thyroid Neoplasms

keytruda lenvima

Rating

72/100

70/100

Pharmacy pays

—

Type

Active ingredient

PEMBROLIZUMAB

LENVATINIB MESYLATE

Manufacturer

Merck Sharp Dohme

Eisai Inc

Dosage forms

Injectable

Capsule, Kit

Drug class

Programmed Death Receptor-1 Blocking Antibody

—

Boxed warning

None

Treats

Malignant Mesothelioma, Biliary Tract Neoplasms, Urinary Bladder Neoplasms

Renal Cell Carcinoma, Thyroid Neoplasms

Frequently asked questions

Which is better-rated, Keytruda or Lenvima?

By our independent rating, Keytruda scores higher — 3.6 vs 3.5 out of 5 for Lenvima. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Keytruda and Lenvima?

Keytruda contains Pembrolizumab, while Lenvima contains Lenvatinib Mesylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.