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KEPPRA XR vs SEZABY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. KEPPRA XR and SEZABY are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

keppra xrsezaby

Rating

70/100
New

Pharmacy pays

~$2.34 /30
~$3.49 /30

Type

RX
RX

Active ingredient

LEVETIRACETAM
PHENOBARBITAL SODIUM

Manufacturer

Ucb Inc
Sun Pharm Inds Inc

Dosage forms

Tablet, extended release
Injectable

Drug class

—
—

Boxed warning

None
Boxed warning

Half-life

about 7 hours (the label states 7 ± 1 hour in adults)
—

Treats

Partial Epilepsies, Tonic-Clonic Epilepsy, Juvenile Myoclonic Epilepsy
Febrile Seizures, Partial Epilepsies, Tonic-Clonic Epilepsy

Frequently asked questions

Which is cheaper, Keppra XR or Sezaby?

Keppra XR costs pharmacies less to acquire — about $2.34 vs $3.49 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Keppra XR and Sezaby?

Keppra XR contains Levetiracetam, while Sezaby contains Phenobarbital Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.